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Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody P41827.
Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin-L1 antiobdy P41827. The lane on the left is treated with systhesized peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin-L1 antibody P41827.

Rabbit Polyclonal Antibody to Cyclin-L1

  • 货号:

    P41827
  • 别名:

    Cyclin-L; CCNL1;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9UK58
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to Cyclin-L1

Description

Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152.Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S篓鹿sse, Nucleic Acids Res., Feb 2004; 32: 669 - 680.

Specification

Aliases Cyclin-L; CCNL1;
Entrez GeneID 57018;
Swissprot Q9UK58
WB Predicted band size 60kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from human Cyclin-L1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100