Rabbit Polyclonal Antibody to 45202

Description
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

References
Y Saijoh, Genes Cells, Feb 1996; 1: 239 - 252. Christopher L. Shaffer, Drug Metab. Dispos., Apr 2007; 10.1124 Brian Boer, Nucleic Acids Res., Mar 2007; 35: 1773 - 1786. E Pikarsky, Mol. Cell. Biol., Feb 1994; 14: 1026 - 1038.

Specification
Aliases	41915; OCT4; OTF3; OTF4; OCTAMER-BINDING TRANSCRIPTION FACTOR 3
Entrez GeneID	5460;
Swissprot	Q01860
WB Predicted band size	50kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from human OCT3 antibody.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000
IHC	1/50-1/100