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Western blot analysis of extracts from COS7 cells, using E2F4 antibody P41798.
Western blot analysis of extracts from JK cells (Lane 2), using E2F4 antiobdy P41798. The lane on the left is treated with synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using E2F4 antibody P41798.

Rabbit Polyclonal Antibody to E2F4

  • 货号:

    P41798
  • 别名:

    E2F-4; p107/p130-binding protein;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q16254
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to E2F4

Description

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1.Kathryn M. Kinross, Blood, Aug 2006; 108: 886 - 895.Dawei Wang, Mol. Cell. Biol., May 2000; 20: 3417 - 3424.Stephan P. Persengiev, Mol. Cell. Biol., Sep 1999; 19: 6048 - 6056.Stefan Gaubatz, Mol. Cell. Biol., Feb 2001; 21: 1384 - 1392.

Specification

Aliases E2F-4; p107/p130-binding protein;
Entrez GeneID 1874;
Swissprot Q16254
WB Predicted band size 44kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from human E2F4.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41798