Rabbit Polyclonal Antibody to p47 phox (Ab-345)

Description
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).Volpp B.D., Proc. Natl. Acad. Sci. U.S.A. 86:7195-7199(1989).Lomax K.J., Science 245:409-412(1989).Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).

Specification
Aliases	47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-1; NCF-47K; NCF1
Entrez GeneID	653361;
Swissprot	P14598
WB Predicted band size	45kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human p47 phox around the phosphorylation site of serine 345 (P-Q-S(p)-P-G).
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000
IHC	1/50-1/100