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Western blot analysis of extracts from COS cells, using GAB2 (Ab-159) antibody P41736.

Western blot analysis of extracts from 293 cells (Lane 2), using GAB2 (Ab-159) antiobdy P41736. The lane on the left is treated with synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GAB2 (Ab-159) antibody P41736.

Rabbit Polyclonal Antibody to GAB2 (Ab-159)

货号：
P41736
别名：
GABJ; GRB2-associated binding protein 2; KIAA0571; pp100;
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UQC2
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to GAB2 (Ab-159)

Description
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis

Description

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis

References
Nishida K., Blood 93:1809-1816(1999) Nagase T., DNA Res. 5:31-39(1998) Taylor T.D., Nature 440:497-500(2006).

Specification
Aliases	GABJ; GRB2-associated binding protein 2; KIAA0571; pp100;
Entrez GeneID	9846;
Swissprot	Q9UQC2
WB Predicted band size	97kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human GAB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P).
Formulation	Purified antibody in PBS with 0.05% sodium azide.