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Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody P41729.
Western blot analysis of extracts from colo cells (Lane 2), using TTK (Ab-676) antiobdy P41729. The lane on the left is treated with synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody P41729.

Rabbit Polyclonal Antibody to TTK (Ab-676)

  • 货号:

    P41729
  • 别名:

    dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P33981
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to TTK (Ab-676)

Description

Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.Mills G.B., J. Biol. Chem. 267:16000-16006(1992).Ota T., Nat. Genet. 36:40-45(2004).Mungall A.J., Nature 425:805-811(2003)

Specification

Aliases dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1
Entrez GeneID 7272;
Swissprot P33981
WB Predicted band size 100kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V).
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100