Rabbit Polyclonal Antibody to ITGB4 (Ab-1510)

Description
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.Suzuki S., EMBO J. 9:757-763(1990).Hogervorst F., EMBO J. 9:765-770(1990).Tamura R.N., J. Cell Biol. 111:1593-1604(1990).

Specification
Aliases	CD104 antigen; GP150; ITB4; integrin beta-4; integrin beta-4C
Entrez GeneID	3691;
Swissprot	P16144
WB Predicted band size	202kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T).
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000
IHC	1/50-1/100