Rabbit Polyclonal Antibody to Smad1 (Ab-187)

Description
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1

References
Riggins G.J., Nat. Genet. 13:347-349(1996) Liu F., Nature 381:620-623(1996) Hoodless P.A., Cell 85:489-500(1996)

Specification
Aliases	BSP-1; BSP1; Dwarfin-A; Dwf-A; JV4-1
Entrez GeneID	4086;
Swissprot	Q15797
WB Predicted band size	60kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human Smad1 around the phosphorylation site of serine 187 (P-H-S(p)-P-N).
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/3000
IF/ICC	1/100-1/500