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Gel: 10%SDS-PAGE Lane1: Human liver cancer tissue lysate Lane2: Human breast infiltrative duct tissue lysate Lane3: Human fetal brain tissue lysate Lysate: 27ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes

The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using 31278 (AKR1C1 Antibody) at dilution 1/30, on the right is treated with the synthetic peptide.

Rabbit Polyclonal Antibody to AKR1C1

货号：
P41629
别名：
Aldo-keto reductase family 1, member C1, C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
Q04828
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to AKR1C1

Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Specification
Aliases	Aldo-keto reductase family 1, member C1, C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
Entrez GeneID	1645;
Swissprot	Q04828
WB Predicted band size	37kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Synthetic peptide corresponding to a region derived from 290-304 amino acids of human aldo-keto reductase family 1, member C1
Formulation	Purified antibody in PBS with 0.05% sodium azide.