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Gel: 10%SDS-PAGE Lane1: 231 cell lysateLane2: 293T cell lysateLane3: Hela cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 10 seconds

Rabbit Polyclonal Antibody to EPOR

货号：
P41622
别名：
erythropoietin receptor, EPO-R
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P19235
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to EPOR

Description
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Description

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Specification
Aliases	erythropoietin receptor, EPO-R
Entrez GeneID	2057;
Swissprot	P19235
WB Predicted band size	55kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Synthetic peptide corresponding to a region derived from 31-45 amino acids of Human erythropoietin receptor
Formulation	Purified antibody in PBS with 0.05% sodium azide.