Rabbit Polyclonal Antibody to c-kit(Ab-936)

Description
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

References
Martin, F.H. et al. (1990) Cell 63, 203-11.Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62.Gommerman, J.L. et al. (1997) J Biol Chem 272, 30519-25.Nocka, K. et al. (1990) EMBO J 9, 1805-13.

Specification
Aliases	KIT; CD117; SCFR; PBT;
Entrez GeneID	3815;
Swissprot	P10721
WB Predicted band size	145kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100