Rabbit Polyclonal Antibody to 45203

Description
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

References
Pesce, M. and Scholer, H.R. (2001) Stem Cells 19, 271-278. Pan, G. and Thomson, J.A. (2007) Cell Res 17, 42-9. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91.

Specification
Aliases	Otc3; OTF3; OTF4; OTF-3;
Entrez GeneID	5460;
Swissprot	Q01860
WB Predicted band size	45kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000