Rabbit Polyclonal Antibody to IKK-b(Ab-199)

Description
Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.

References
Chen RA, et al. PLoS Pathog. 2008 Feb 8;4(2):e22Yen CJ,et al. Cancer Res. 2008 Apr 15;68(8):2632-40

Specification
Aliases	I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK2; IkBKB; NFKBIKB
Entrez GeneID	3551;
Swissprot	O14920
WB Predicted band size	87kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-b.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IF	1/100-1/200