提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388787

首页 > 产品中心 > 产品详情

Western blot analysis of extracts from HT29 cells using NFkB-p100(Ab-872) Antibody P41486 and the same antibody preincubated with blocking peptide.

Immunofluorescence staining of methanol-fixed Hela cells using NFkB-p100(Ab-872) Antibody P41486.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NFkB-p100/p52(Ab-872) Antibody P41486(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to NFkB-p100(Ab-872)

货号：
P41486
别名：
DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q00653
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

分享
咨询
收藏

加入购物车

立即购买

Rabbit Polyclonal Antibody to NFkB-p100(Ab-872)

Description
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Description

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

References
Shin HM, et al. (2006) EMBO J; 25(1): 129-138. Li Q, et al. (2005) Proc Natl Acad Sci USA; 102(35): 12425-12430. Chen C, et al. (2000) Mol Cell Biol; 20(8): 2687-2695.

Specification
Aliases	DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2
Entrez GeneID	4791;
Swissprot	Q00653
WB Predicted band size	120 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NFkB-p100.
Formulation	Purified antibody in PBS with 0.05% sodium azide.