Rabbit Polyclonal Antibody to IkB-e(Ab-22)

Description
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.

References
Shirane M, et al. (1999) J Biol Chem; 274(40): 28169-74Karin, M. and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. ;18, 621-663.Chen, Z.J. et al. (1996) Cell; 84, 853-862.Brown, K. et al. (1995) Science; 267, 1485-1488.

Specification
Aliases	I-kappa-B-epsilon
Entrez GeneID	4794;
Swissprot	O00221
WB Predicted band size	40kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa. 20~24 (I-E-S-L-R) derived from Human IkB-e.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100