Rabbit Polyclonal Antibody to Synaptotagmin 1/2 (Ab-202/199)

Description
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

References
Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18(5):1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18(12):4957-68.

Specification
Aliases	SYT1/2; SytI/II; Synaptotagmin I/II; P65; SYT
Entrez GeneID	6857;
Swissprot	P21579
WB Predicted band size	46kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.200~204/197~201 (R-K-T-L-N) derived from Human Synaptotagmin 1/2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IF	1/100-1/200