提醒成功

QQ登录

微信登录

同意并阅读使用条款和隐私策略

账号密码登录

微信/QQ登录

没有账号？立即注册

搜索

抗体销售咨询健康评估咨询 mRNA-LNP咨询

0731-88388787

首页 > 产品中心 > 产品详情

Western blot analysis of extracts from PC12 cells using PKCth(Ab-676) Antibody P41480.

Immunofluorescence staining of methanol-fixed Hela cells using PKCth(Ab-676) Antibody P41480.

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PKCth(Ab-676) Antibody P41480(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to PKCth(Ab-676)

货号：
P41480
别名：
nPKC-theta
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q04759
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

分享
咨询
收藏

加入购物车

立即购买

Rabbit Polyclonal Antibody to PKCth(Ab-676)

Description
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

Description

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

References
Kristof Van Kolen, et al. (2006) FEBS J ; 273: 1843 - 1854.Martin Villalba, et al. (2002) J. Cell Biol ; 157: 253. Jie Zhang, et al. (2004) J. Biol. Chem ; 279: 22118 - 22123. Castro AF, et al. (1998) Am J Physiol Cell Physiol; 275: C113 - C119.

Specification
Aliases	nPKC-theta
Entrez GeneID	5588;
Swissprot	Q04759
WB Predicted band size	80kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa. 674~678 (R-L-S-F-A) derived from Human PKCth.
Formulation	Purified antibody in PBS with 0.05% sodium azide.