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Western blot analysis of extracts from PC12 cells using PKCd(Ab-645) Antibody P41479.

Immunofluorescence staining of methanol-fixed Hela cells using PKCd(Ab-645) Antibody P41479.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PKCd(Ab-645) Antibody P41479(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to PKCd(Ab-645)

货号：
P41479
别名：
nPKC-delta
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q05655
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PKCd(Ab-645)

Description
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Description

This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

References
Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab, ; 285: E1081 - E1088. Ling Zhang, et,al. (2004) J. Biol. Chem ; 279: 28315 - 28319. Kristof Van Kolen et,al. (2006) FEBS J ; 273: 1843 - 1854. Martin Villalba, et,al. (2002) J. Cell Biol ; 157: 253.

Specification
Aliases	nPKC-delta
Entrez GeneID	5580;
Swissprot	Q05655
WB Predicted band size	78kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa. 643~647 (R-L-S-Y-S) derived from Human PKCd.
Formulation	Purified antibody in PBS with 0.05% sodium azide.