Rabbit Polyclonal Antibody to CPI17a(Ab-38)

Description
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

References
Hagerty L, et al. (2007) J Biol Chem. 2007; 282(7):4884-93Seok YM, et al. (2008) J Pharmacol Exp Ther. Niiro N et al. (2003) Biochem J. 2003 ;369(Pt 1):117-28

Specification
Aliases	CPI; CPI-17; CPI17; PP14A;
Entrez GeneID	94274;
Swissprot	Q96A00
WB Predicted band size	17kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IF	1/100-1/200