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Western blot analysis of extracts from 293, Hela and C6 cells using PKR(Ab-446) Antibody P41464.

Immunofluorescence staining of methanol-fixed Hela cells using PKR(Ab-446) Antibody P41464.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PKR(Ab-446) Antibody P41464(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to PKR(Ab-446)

货号：
P41464
别名：
ADRB2; E2AK2; EIF2AK2; EIF2aK; PRKR
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P19525
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PKR(Ab-446)

Description
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

References
Abujiang Pataer, et,al. (2002) Cancer Res ; 62: 2239.K. D. Ryman, et,al. (2005) J. Virol ; 79: 1487 - 1499.Susana Guerra, et,al. (2006) J. Biol. Chem ; 281: 18734 - 18745.

Specification
Aliases	ADRB2; E2AK2; EIF2AK2; EIF2aK; PRKR
Entrez GeneID	5610;
Swissprot	P19525
WB Predicted band size	68kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Peptide sequence around aa.444~448 (K-R-T-R-S) derived from Human PKR.
Formulation	Purified antibody in PBS with 0.05% sodium azide.