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Western blot analysis of extracts from JK cells using p56Dok-2(Ab-299) Antibody P41463.

Immunofluorescence staining of methanol-fixed Hela cells using p56Dok-2(Ab-299) Antibody P41463.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p56Dok-2(Ab-299) Antibody P41463(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p56Dok-2(Ab-299)

货号：
P41463
别名：
DOK2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O60496
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to p56Dok-2(Ab-299)

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

References
Feng Cong, et,al. (1999) Mol. Cell. Biol; 19: 8314 - 8325.Serge Lemay, et,al. (2000) Mol. Cell. Biol; 20: 2743 - 2754.Ute Schaeper, et,al.(2000) J. Cell Biol; 149: 1419.Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151.

Specification
Aliases	DOK2
Entrez GeneID	9046;
Swissprot	O60496
WB Predicted band size	56kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2.
Formulation	Purified antibody in PBS with 0.05% sodium azide.