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Western blot analysis of extracts from K562, HL-60 and JK cells using p62Dok(Ab-398) Antibody P41462.

Immunofluorescence staining of methanol-fixed Hela cells using p62Dok(Ab-398) Antibody P41462.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok(Ab-398) Antibody P41462(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to p62Dok(Ab-398)

货号：
P41462
别名：
DOK1
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99704
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to p62Dok(Ab-398)

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

References
Michael J. Wick,et,al. (2001) J. Biol. Chem; 276: 42843 - 42850.Paul D. Simoncic, et,al. (2006) Mol. Cell. Biol; 26: 4149 - 4160.Nadia Dub

Specification
Aliases	DOK1
Entrez GeneID	1796;
Swissprot	Q99704
WB Predicted band size	62kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.396~400 (P-I-Y-D-E) derived from Human p62Dok.
Formulation	Purified antibody in PBS with 0.05% sodium azide.