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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using KCNN4 mouse mAb against HepG2 (1), Jurkat (2), Hela (3), MCF-7 (4), HEK293 (5), SW480 (6), HT-29 (7), and SW620 (8) cell lysate.

Flow cytometric analysis of THP-1 cells using KCNN4 mouse mAb (green) and negative control (red).

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Mouse Monoclonal Antibody to KCNN4

货号：
32182
别名：
IK; IK1; SK4; DHS2; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1
产品上架时间：
2024-01-01
应用：
WB,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O15554
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to KCNN4

Description
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Description

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

References
1.Exp Cell Res. 2018 Aug 15;369(2):208-217. 2.Sci Signal. 2018 Apr 24;11(527):eaaq1616.

Specification
Aliases	IK; IK1; SK4; DHS2; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1
Entrez GeneID	3783
Swissprot	O15554
clone	2B1G1
WB Predicted band size	47.6kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human KCNN4 (AA: extra 286-427) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide