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Western blot analysis of extracts from HepG2 , Hela and 293 cells using 14-3-3z(Ab-58) Antibody P41394.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 14-3-3z(Ab-58) Antibody P41394(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to 14-3-3z(Ab-58)

货号：
P41394
别名：
1433Z; 143Z; FAS; Factor activating exoenzyme S; KCIP-1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P63104
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to 14-3-3z(Ab-58)

Description
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

References
Gu YM, et al. (2006) FEBS Lett ; 580(1): 305-310Powell DW, et al. (2003) Mol Cell Biol; 23(15): 5376-5387Mackintosh C. (2004) Biochem J; 381(Pt 2): 329-342.

Specification
Aliases	1433Z; 143Z; FAS; Factor activating exoenzyme S; KCIP-1
Entrez GeneID	7534;
Swissprot	P63104
WB Predicted band size	28kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.56~60 (R-S-S-W-R) derived from Human 14-3-3 zeta.
Formulation	Purified antibody in PBS with 0.05% sodium azide.