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Western blot analysis of extracts from 293 cells using MEK1(Ab-221) Antibody P41385
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK1(Ab-221) Antibody P41385(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to MEK1(Ab-221)

  • 货号:

    P41385
  • 别名:

    ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q02750
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to MEK1(Ab-221)

Description

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

References

Zebisch A, et al. (2006) Cancer Res; 66(7): 3401-8.Luciano BS, et al. (2006)J Biol Chem; 279(50): 52117-23.Wang X, et al. (2003) Oncogene; 22(1): 109-16.Gopalbhai K, et al. (2003) J Biol Chem; 278(10): 8118-25.Ling MT, et al. (2002)Oncogene; 21(55): 8498-505.

Specification

Aliases ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1
Entrez GeneID 5604;
Swissprot Q02750
WB Predicted band size 45kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around aa.219~223 (A-N-S-F-V) derived from Human MEK1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P41385