Rabbit Polyclonal Antibody to cofilin(Ab-3)

Description
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

References
Kobayashi M, et al. (2006) EMBO J 25(4): 713-26. Wang Y, et al. (2005)Biol Chem 280(13): 12683-9. Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.

Specification
Aliases	CFL; CFL1; COF1; Cofilin;
Entrez GeneID	1072;
Swissprot	P23528
WB Predicted band size	19kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100