Rabbit Polyclonal Antibody to CDC2(Ab-161)

Description
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

References
Ukomadu C, et al.(2003) J Biol Chem; 278(7): 4840-6Morris MC, et al.(2002)J Biol Chem; 277(26): 23847-53Brown NR, et al.(1999)J Biol Chem; 274(13): 8746-56Liu Y, et al.(2004) J Biol Chem; 279(6): 4507-14

Specification
Aliases	CDC28; CDC2A; CDK1; Cyclin-dependent kinase 1;
Entrez GeneID	983;
Swissprot	P06493
WB Predicted band size	34kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.159~163 (T-Y-T-H-E) derived from Human CDC2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000
IF/ICC	1/100-1/200