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Western blot analysis of extracts from HT29 cells using cdc25C(Ab-216) Antibody P41360 and the same antibody preincubated with blocking peptide.
Immunofluorescence staining of methanol-fixed Hela cells using cdc25C(Ab-216) Antibody P41360.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cdc25C(Ab-216) Antibody P41360(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to cdc25C(Ab-216)

  • 货号:

    P41360
  • 别名:

    CDC25M1; MPIP3;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P30307
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to cdc25C(Ab-216)

Description

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded

References

protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348.Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860.Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677.Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995.

Specification

Aliases CDC25M1; MPIP3;
Entrez GeneID 995;
Swissprot P30307
WB Predicted band size 60kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200