Rabbit Polyclonal Antibody to IGF-1R(Ab-1165/1166)

Description
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

References
Li S, et al. (1994) J Biol Chem; 269(51): 32558-64.

Specification
Aliases	Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
Entrez GeneID	3480;
Swissprot	P08069
WB Predicted band size	200 95 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.1163~1167/1164~1168 (T-D-Y-Y-R-K) derived from Human IGF-1R .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000