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Western blot analysis of extracts from 293 cells using IGF-1R(Ab-1161) Antibody P41307 and the same antibody preincubated with blocking peptide.

Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R(Ab-1161) Antibody P41307.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R(Ab-1161) Antibody P41307(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to IGF-1R(Ab-1161)

货号：
P41307
别名：
Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P08069
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to IGF-1R(Ab-1161)

Description
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

References
Li S, et al. (1994) J Biol Chem; 269(51). Hernandez-Sanchez C, et al. (1995) J Biol Chem.

Specification
Aliases	Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
Entrez GeneID	3480;
Swissprot	P08069
WB Predicted band size	200 95 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Formulation	Purified antibody in PBS with 0.05% sodium azide.