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Western blot analysis of extracts from 293 and Hela cells using BCL-XL(Ab-62) antibody P41289.
Rabbit Polyclonal Antibody to BCL-XL(Ab-62)
-
货号：
P41289 -
别名：
Apoptosis regulator Bcl-X -
应用：
WB -
反应种属：
Human,Mouse,Rat -
抗体类型：
Primary antibody -
Swissprot：
Q07817 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to BCL-XL(Ab-62)
Description |
|---|
Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. |
References |
|---|
| Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7Cheng E.H.-Y. et.al. (1996) Nature 379:554-556.Sattler M. et.al. (1997), Science 275:983-986.Muchmore S.W.et.al (1996).Nature 381:335-341Yu J., Zhang L. Mol. (2001)Cell 7:673-682 |
Specification |
|
|---|---|
| Aliases | Apoptosis regulator Bcl-X |
| Entrez GeneID | 598; |
| Swissprot | Q07817 |
| WB Predicted band size | 30kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL . |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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