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Rabbit Polyclonal Antibody to BCL-2(Ab-70)

Western blot analysis of extracts from MCF cells using BCL-2(Ab-70) Antibody P41288 and the same antibody preincubated with blocking peptide.

Immunofluorescence staining of methanol-fixed Hela cells using BCL-2(Ab-70) Antibody P41288.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BCL-2(Ab-70) Antibody P41288(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to BCL-2(Ab-70)

货号：
P41288
别名：
BCL2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P10415
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to BCL-2(Ab-70)

Description
BCL-2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

References
Muller IM, et al. (2005) Mol Pharmacol.Jin Z, Gao F,et al. J Biol Chem 2004 Sep 17; 279(38): 40209-19.Kumar Biswas S,et al. Mol Cancer Ther 2004 Mar; 3(3): 327-34.Huang ST,et al. (2002)FASEB J; 16(8): 825-32.Yamamoto K,et al. (1999) Mol Cell Biol; 19(12): 8469-78.

Specification
Aliases	BCL2
Entrez GeneID	596;
Swissprot	P10415
WB Predicted band size	26kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa.68~72 (R-T-S-P-L) derived from Human BCL-2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.