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Rabbit Polyclonal Antibody to BCL-2(Ab-56)

Western blot analysis of extracts from Hela, A2780 and 293 cells using BCL-2(Ab-56) Antibody P41287.

Immunofluorescence staining of methanol-fixed Hela cells using BCL-2(Ab-56) Antibody P41287.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BCL-2(Ab-56) Antibody P41287(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to BCL-2(Ab-56)

货号：
P41287
别名：
BCL2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P10415
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to BCL-2(Ab-56)

Description
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Description

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

References
Ling, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991.Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832.Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688.Huang ST,et al. (2002) FASEB J Jun; 16(8): 825-32.Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.

Specification
Aliases	BCL2
Entrez GeneID	596;
Swissprot	P10415
WB Predicted band size	26kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around aa. 54~58 (G-H-T-P-H) derived from Human BCL-2.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.