Mouse Monoclonal Antibody to BCL2

Description
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

References
1.Nucleic Acids Res. 2020 Dec 16;48(22):12727-12745. 2.Prog Transplant. 2020 Jun;30(2):184-186.

Specification
Aliases	Bcl-2; PPP1R50
Entrez GeneID	596
Swissprot	P10415
clone	3B5H7
WB Predicted band size	26.3kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat
Immunogen	Purified recombinant fragment of human BCL2 (AA: 1-239) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
FCM	1/200 - 1/400
ELISA	1/10000