Rabbit Polyclonal Antibody to STAT3(Ab-705)

Description
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

References
Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120.Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804.Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115.Garcia R, et al. (1998) J Biomed Sci. 5: 79-85.Bromberg J F, et al. (1999) Cell. 98: 295-303.

Specification
Aliases	APRF; Acute-phase response factor; HIES
Entrez GeneID	6774;
Swissprot	P40763
WB Predicted band size	88kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.703~707(A-P-Y-L-K) derived from Human STAT3.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100
IF	1/100-1/200