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Western blot analysis of extracts from HT29 cells using NFkB-p100(Ab-866) Antibody P41251.

Immunofluorescence staining of methanol-fixed Hela cells using NFkB-p100(Ab-866) Antibody P41251.

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB-p100(Ab-866) Antibody P41251(left) or the same antibody preincubated with blocking peptide(right).

Rabbit Polyclonal Antibody to NFkB-p100(Ab-866)

货号：
P41251
别名：
DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q00653
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to NFkB-p100(Ab-866)

Description
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Description

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

References
Qu Z, et al. (2004) J Biol Chem. 279(43): 44563-44572. Xiao G, et al. (2001) Mol Cell. 7(2): 401-409. Baeuerle P A, et al. (1994) Annu Rev Immunol. 12:141-179. Baeuerle P A, et al. (1996) Cell 87:13-20. Haskill S, et al. (1991) Cell 65:1281-1289.

Specification
Aliases	DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2
Entrez GeneID	4791;
Swissprot	Q00653
WB Predicted band size	120 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NFkB-p100.
Formulation	Purified antibody in PBS with 0.05% sodium azide.