Rabbit Polyclonal Antibody to PDK1(Ab-241)

Description
Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development

References
Scheid MP,et al. (2005)Mol Cell Biol; 25(6): 2347-63Chen H, et al. (2001) Biochemistry; 40(39): 11851-9Sato S,et al. (2002) J Biol Chem; 277(42): 39360-7Lim MA, et al.(2003)Proc Natl Acad Sci U S A; 100(24): 14006-11Beausoleil SA, et al. (2004)Proc Natl Acad Sci U S A; 101(33): 12130-5

Specification
Aliases	PDPK1, PkB kinase, Protein kinase B kinase, hPDK1, kinase PDK1
Entrez GeneID	5170;
Swissprot	O15530
WB Predicted band size	63kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around aa.239~243 (A-N-S-F-V) derived from Human PDK1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IHC	1/50-1/100
IF	1/100-1/200