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Rabbit Polyclonal Antibody to RB(Phospho-Ser811)
Western blot analysis of extracts of HeLa cells, using Phospho-RB-S811 antibody.
Rabbit Polyclonal Antibody to RB(Phospho-Ser811)

Rabbit Polyclonal Antibody to RB(Phospho-Ser811)

  • 货号:

    P40769
  • 别名:

    OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P06400
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to RB(Phospho-Ser811)

Description

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Specification

Aliases OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Entrez GeneID 5925
Swissprot P06400
WB Predicted band size 106kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthetic phosphorylated peptide around S811 of human RB (NP_000312.2).
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application

WB 1/1000-1/2000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P40769