提醒成功
微信/QQ登录
搜索
首页
Western blot analysis of extracts of 293 cell line, using phospho-MDM2-S260 antibody.
Rabbit Polyclonal Antibody to MDM2(Phospho-Ser260)
-
货号：
P40767 -
别名：
HDMX; hdm2; ACTFS; MGC5370; MGC71221 -
应用：
WB -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q00987 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to MDM2(Phospho-Ser260)
Description |
|---|
MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 (1). Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 (2-4). Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 (3). |
Specification |
|
|---|---|
| Aliases | HDMX; hdm2; ACTFS; MGC5370; MGC71221 |
| Entrez GeneID | 4193; |
| Swissprot | Q00987 |
| WB Predicted band size | 95kDa;55kDa(Calculated) |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S260 of human MDM2. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/2000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P40767
相关产品
联系方式
CONTACT-
联系电话:
0731-88388785 -
公司邮箱:
sales@promab.cn -
公司地址:
湖南省长沙市高新开发区林语路239号顺畅产业园5楼
官方微信
产品中心
Product技术服务
service客户留言
message