Rabbit Polyclonal Antibody to 53BP1 (Phospho-Ser25)

Description
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

Specification
Aliases	P531; TP53B; TP53BP1; TRP53BP1; Tumor suppressor p53-binding protein 1; p53-binding protein 1
Entrez GeneID	7158;
Swissprot	Q12888
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of serine 25 (E-D-S(p)-Q-P) derived from Human 53BP1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
IHC	1/50-1/100
IF	1/100-1/500