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Immunohistochemistry analysis of paraffin-embedded human brain tissue using AurB/C (Phospho-Thr236/202) antibody P40716. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal Antibody to AurB/C (Phospho-Thr236/202)

货号：
P40716
别名：
AIE1; AIE2; AURKC; Aurora-C; Aurora/Ipl1-related kinase 3; Aurora/Ipl1/Eg2 protein 1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; STK13; STKD; Serine/threonine protein kinase 13; kinase AIK3
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q9UQB9
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to AurB/C (Phospho-Thr236/202)

Description
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.

Description

Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.

Specification
Aliases	AIE1; AIE2; AURKC; Aurora-C; Aurora/Ipl1-related kinase 3; Aurora/Ipl1/Eg2 protein 1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; STK13; STKD; Serine/threonine protein kinase 13; kinase AIK3
Entrez GeneID	6795;
Swissprot	Q9UQB9
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C.
Formulation	Purified antibody in PBS with 0.05% sodium azide.