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Western blot analysis of extracts from COS-7 cells using I kappaB- alpha (Phospho-Tyr305) Antibody P40669.The lane on the left is treated with the antigen-specific peptide.
Rabbit Polyclonal Antibody to I kappaB- alpha (Phospho-Tyr305)
-
货号：
P40669 -
别名：
IKBA, MAD-3, NFKBI -
应用：
WB -
反应种属：
Human,Mouse,Rat Monkey -
抗体类型：
Primary antibody -
Swissprot：
P25963 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to I kappaB- alpha (Phospho-Tyr305)
Description |
|---|
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
Specification |
|
|---|---|
| Aliases | IKBA, MAD-3, NFKBI |
| Entrez GeneID | 4792; |
| Swissprot | P25963 |
| WB Predicted band size | 39kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat Monkey |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 305(L-P-Y(p)-D-D) derived from Human I kappaB- alpha. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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0731-88388785 -
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sales@promab.cn -
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