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Rabbit Polyclonal Antibody to IkappaB- beta (Phospho-Thr19)

Western blot analysis of extracts from Mouse brain tissue using IkappaB- beta (Phospho-Thr19) Antibody P40640.The lane on the left is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to IkappaB- beta (Phospho-Thr19)

货号：
P40640
别名：
IKBB, TRIP9
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q15653
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to IkappaB- beta (Phospho-Thr19)

Description
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Description

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Specification
Aliases	IKBB, TRIP9
Entrez GeneID	4793;
Swissprot	Q15653
WB Predicted band size	37kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Threonine 19 (C-D-S(p)-G-L) derived from Human IkappaB- beta.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.