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Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) antibody P40618.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to HDAC6 (Phospho-Ser22)

货号：
P40618
别名：
HD6; HDA6; Histone deacetylase 6; JM21;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UBN7
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to HDAC6 (Phospho-Ser22)

Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes By similarity. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.Chen S, Owens GC, Makarenkova H, Edelman DB (2010)PLoS One 5, e10848.

Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes By similarity. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.Chen S, Owens GC, Makarenkova H, Edelman DB (2010)PLoS One 5, e10848.

Specification
Aliases	HD6; HDA6; Histone deacetylase 6; JM21;
Entrez GeneID	10013;
Swissprot	Q9UBN7
WB Predicted band size	131kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Peptide sequence around phosphorylation site of serine 22 (P-Q-S(p)-P-P) derived from Human HDAC6.
Formulation	Purified antibody in PBS with 0.05% sodium azide.