Rabbit Polyclonal Antibody to Vinculin (Phospho-Tyr822)

Description
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion

References
Subauste MC, et al. (2004) J Cell Biol 165, 371-81 Olsen JV, et al. (2010) Sci Signal 3, ra3 J?rgensen C, et al. (2009) Science 326, 1502-9

Specification
Aliases	Vinculin;
Entrez GeneID	7414;
Swissprot	P18206
WB Predicted band size	123kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Tyrosine 822 (S-G-Y(p)-R-I) derived from Human Vinculin.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000