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Rabbit Polyclonal Antibody to Smad3 (Phospho-Thr179)

Western blot analysis of extracts from HeLa cells treated with TNF using Phospho-Smad3 (Thr179) antibody P40591.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to Smad3 (Phospho-Thr179)

货号：
P40591
别名：
JV15-2; MAD-3; MADH3; Smad 3; Mothers against decapentaplegic homolog 3
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P84022
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to Smad3 (Phospho-Thr179)

Description
Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24 Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol Cancer Res 8, 1375-87 Matsuura I, et al. (2010) J Biol Chem 285, 1754-64

Description

Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24 Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol Cancer Res 8, 1375-87 Matsuura I, et al. (2010) J Biol Chem 285, 1754-64

Specification
Aliases	JV15-2; MAD-3; MADH3; Smad 3; Mothers against decapentaplegic homolog 3
Entrez GeneID	4088;
Swissprot	P84022
WB Predicted band size	50kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine179(P-E-T(p)-P-P) derived from Human Smad3 .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.