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Rabbit Polyclonal Antibody to SREBP-1 (Phospho-Ser439)

Western blot analysis of extracts from Jurkat cells treated with TNF using Phospho-SREBP-1 (Ser439) antibody P40588.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to SREBP-1 (Phospho-Ser439)

货号：
P40588
别名：
SRBP1; SREBF1; SREBP1; sterol regulatory element-binding protein 1;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P36956
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to SREBP-1 (Phospho-Ser439)

Description
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway By similarity. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').Bengoechea-Alonso MT, Ericsson J (2006) Cell Cycle 5, 1708-18

Description

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway By similarity. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').Bengoechea-Alonso MT, Ericsson J (2006) Cell Cycle 5, 1708-18

Specification
Aliases	SRBP1; SREBF1; SREBP1; sterol regulatory element-binding protein 1;
Entrez GeneID	6720;
Swissprot	P36956
WB Predicted band size	122kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of serine439(Q-S-S(p)-P-L) derived from Human SREBP-1 .
Formulation	Purified antibody in PBS with 0.05% sodium azide.