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Rabbit Polyclonal Antibody to VE-Cadherin (Phospho-Tyr731)

Western blot analysis of extracts from HepG2 cells treated with Na3VO4 using Phospho-VE-Cadherin (Tyr731) antibody P40587.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to VE-Cadherin (Phospho-Tyr731)

货号：
P40587
别名：
Vascular endothelial cadherin; VE-cadherin; 7B4 antigen; CDH5; CD144 antigen
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P33151
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to VE-Cadherin (Phospho-Tyr731)

Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. Wessel F, et al. (2014) Nat Immunol 15, 223-30 Sawada J, et al. (2012) Cancer Cell 22, 235-49 Turowski P, et al. (2008) J Cell Sci 121, 29-37

Description

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. Wessel F, et al. (2014) Nat Immunol 15, 223-30 Sawada J, et al. (2012) Cancer Cell 22, 235-49 Turowski P, et al. (2008) J Cell Sci 121, 29-37

Specification
Aliases	Vascular endothelial cadherin; VE-cadherin; 7B4 antigen; CDH5; CD144 antigen
Entrez GeneID	1003;
Swissprot	P33151
WB Predicted band size	130kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.