Rabbit Polyclonal Antibody to CDC25A (Phospho-Ser178)

Description
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

References
Chen MS, Ryan CE, Piwnica-Worms H (2003)Mol Cell Biol 23, 7488-97 Hassepass I, Voit R, Hoffmann I (2003) J Biol Chem 278, 29824-9 S?rensen CS, et al. (2003) Cancer Cell 3, 247-58

Specification
Aliases	CDC25M3; MPIP1; Dual specificity phosphatase Cdc25A; M-phase inducer phosphatase 1;
Entrez GeneID	993;
Swissprot	P30304
WB Predicted band size	59kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of serine 178(Q-N-S(p)-A-P) derived from Human CDC25A .
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application
WB	1/500-1/1000