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Rabbit Polyclonal Antibody to GR (Phospho-Ser226)

Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-GR (Ser226) antibody P40575.The lane on the right is treated with the antigen-specific peptide.

Rabbit Polyclonal Antibody to GR (Phospho-Ser226)

货号：
P40575
别名：
GCCR; GCR; GRL; NR3C1;
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04150
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to GR (Phospho-Ser226)

Description
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation.Wehmeyer L, Du Toit A, Lang DM, Hapgood JP (2014) J Biol Chem 289, 10235-51 Bouazza B, et al. (2014) Am J Respir Cell Mol Biol 50, 301-15 Lee MS, et al. (2013) Behav Brain Res 236, 56-61

Description

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation.Wehmeyer L, Du Toit A, Lang DM, Hapgood JP (2014) J Biol Chem 289, 10235-51 Bouazza B, et al. (2014) Am J Respir Cell Mol Biol 50, 301-15 Lee MS, et al. (2013) Behav Brain Res 236, 56-61

Specification
Aliases	GCCR; GCR; GRL; NR3C1;
Entrez GeneID	2908;
Swissprot	P04150
WB Predicted band size	86kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of serine 226 (L-L-S(p)-P-L) derived from Human GR.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.